The 2015 ISHLT Guidelines for the Management of Fungal Infections in Mechanical Circulatory Support and Cardiothoracic Organ Transplant Recipients: Executive Summary

Published 19 January 2016

Shahid Husain, MD, MS; Amparo Sole, MD, PhD; Barbara D. Alexander, MD, MHS; Saima Aslam, MD, MS; Robin Avery, MD; Christian Benden, MD; Eliane M. Billaud, PharmD, PhD; Daniel Chambers, MBBS, MD; Lara Danziger-Isakov, MD; Savitri Fedson, MD; Kate Gould, MD; Aric Gregson, MD; Paolo Grossi, MD, PhD; Denis Hadjiliadis, MD; Peter Hopkins, MD; Me-Linh Luong, MD; Debbie J.E. Marriott, MD; Victor Monforte, MD; Patricia Muñoz, MD, PhD; Alessandro C. Pasqualotto, MD, PhD; Antonio Roman, MD; Fernanda P. Silveira, MD; Jeffrey Teuteberg, MD, MS; Stephen Weigt, MD; Aimee K. Zaas, MD, MHS; Andreas Zuckerman, MD; Orla Morrissey, MD, PhD

J Heart Lung Transplant. 2016 Mar;35(3):261-82

• Advanced Heart Failure & Transplantation
• Advanced Lung Failure & Transplantation
• Cardiology
• Cardiothoracic Surgery
• Español
• Executive Summary
• Infectious Diseases
• Mechanical Circulatory Support
• Nursing & Allied Health
• Pathology
• Pediatrics
• Pharmacy
• Professional Guideline
• Publications & Journals
• Pulmonology
• Research & Immunology
• Standards & Guidelines

The field of cardiothoracic transplantation (CT) has evolved significantly, but infections remain an important cause of morbidity and mortality, particularly fungal infections (FIs). The higher mortality associated with FIs has prompted the institution of center-specific anti-fungal prophylactic strategies. In the absence of existing clinical trials, the International Society for Heart and Lung Transplantation (ISHLT) Infectious Diseases Council convened an international and multidisciplinary panel of experts in the field to address the issue.

The panel was divided into working group to specifically focus on epidemiology, diagnosis, prophylaxis, treatment, TDM, and pediatrics. The resulting document summarizes the most current literature in the field of fungal infections related to MCS and heart/lung transplantation.

This document is also available en Español.

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