Report from a Consensus Conference on Primary Graft Dysfunction after Cardiac Transplantation

Published 7 March 2014

Jon Kobashigawa, MD; Andreas Zuckermann, MD; Peter Macdonald, MD, PhD; Pascal Leprince, MD, PhD; Fardad Esmailian, MD; Minh Luu, MBBS; Donna Mancini, MD; Jignesh Patel, MD, PhD; Rabia Razi, MD, MPH; Hermann Reichenspurner, MD, PhD; Stuart Russell, MD; Javier Segovia, MD, PhD; Nicolas Smedira, MD; Josef Stehlik, MD, MPH; Florian Wagner, MD, PhD

J Heart Lung Transplant. 2014 Apr; 33(4):327-40

  • Advanced Heart Failure & Transplantation
  • Anesthesiology & Critical Care
  • Cardiology
  • Cardiothoracic Surgery
  • Consensus Document
  • Publications & Journals
  • Research & Immunology
  • Standards & Guidelines

Although primary graft dysfunction (PGD) is fairly common early after cardiac transplant, standardized schemes for diagnosis and treatment remain contentious. Most major cardiac transplant centers use different definitions and parameters of cardiac function. Thus, there is difficulty comparing published reports and no agreed protocol for management.

A consensus conference was organized and held on 23 April, 2013 in conjunction with the 33rd ISHLT Annual Meeting and Scientific Sessions to formulate guidelines to better define, diagnose, and manage the care of patients with primary graft dysfunction (PGD) in heart transplantation. There were 71 participants (transplant cardiologists, surgeons, immunologists and pathologists), with vast clinical and published experience in PGD, representing 42 heart transplant centers worldwide.

Read at JHLT