October 2023 Journal Watch: Pathology
This month’s ISHLT Journal Watch, a publication from the ISHLT Early Career and Trainee Committee, encapsulates the key themes of progress, innovation, and the changing responsibilities of pathologists in transplantation. In the issue, you’ll read about some of the new, less invasive techniques and technologies that make up the evolving role of the pathologist, which now includes both traditional diagnostic responsibilities and a more integrative role utilizing and interpreting these cutting-edge technologies.
This month’s issue explores:
- The clinical relevance of ddcf-DNA and cfDNA in evaluating patients after lung transplantation.
- If unsupervised gene expression profiling (GEP) can evaluate endomyocardial biopsy using only sequencing data, without relying on histology.
- Comparing the testing accuracy of two ddcf-DNA and GEP products in evaluating heart transplant recipients for acute rejection.
- If club cell secretory protein (CCSP) levels in bronchoalveolar lavage fluid (BALF) can serve as a CLAD biomarker.
- How computer-based deep learning systems can assist in diagnosing or predicting heart transplant rejection.
Issue Editor:
Federica Pezzuto, MD, PhD
University of Padova
Padova, Italy
Additional Contributors:
Nahir Cortes-Santiago, MD, PhD
Texas Children’s Hospital, Baylor College of Medicine
Houston, TX USA
Alessia Giarraputo, MSc, PhD
Paris Institute for Transplantation and Organ Regeneration
Paris, France
Maja Nackenhorst, MD
Medical University of Vienna
Vienna, Austria
Alexander Wein, MD, PhD
Washington University of St. Louis
St. Louis, MO USA
Thanks to issue editor Federica Pezzuto, MD, PhD, and to Paola Morejón Barragán, MD, who translated the issue into Spanish.
Are you an early career professional and looking to contribute to an upcoming issue of Journal Watch? Reach out to Senior Journal Watch Editor Ashley Fritz, DO, at fritz.ashley@mayo.edu.