ISHLT and ISHLT Foundation Fund Research and Career Development With Grants
At ISHLT2023 in Denver, the ISHLT announced more than $400,000 USD in funding for research designed to improve care for patients with advanced heart and lung disease. The grants were funded by the ISHLT Foundation, and are the first of two 2023 ISHLT grant cycles. The second cycle will open at the end of this month.
"I am truly grateful for the strong industry support of our ISHLT research grants,” said Kathleen Grady, PhD, RN, MS, FAAN, Chair of the ISHLT Grants and Awards Committee, “which contribute to scientific breakthroughs in the areas of advanced heart and lung disease across the lifespan and career development of new investigators. Ultimately, these grants inform enhanced patient care.”
“Our industry and non-industry partners in research fully understand the importance and relevance of research to improve outcomes for patients with advanced cardiovascular and pulmonary disease,” said Dr. Grady. “I am very thankful and applaud their support of our grants program.”
Read on for high level details about each winner and their projects.
ISHLT Cardiogenic Shock Research Grant, supported by Abiomed
Awarded to: Thomas Hanff, MD, MS
University of Utah in Salt Lake City, UT USA
Research Title: Angiotensin II Deficiency in Cardiogenic Shock: Using Novel Translational Insights into Cardiogenic Shock Pathophysiology to Guide the Timing and Optimal Use of Temporary Mechanical Circulatory Support
Purpose: The project aims to investigate the role that the renin-angiotensin-aldosterone system plays in cardiogenic shock outcomes.
ISHLT Cardiogenic Shock Research Grant, supported by Abiomed
Awarded to: Paolo Meani, MD, PhD
Maastricht University Medical Center in Maastricht, Netherlands
Research Title: A Multicentric Left Ventricular Venting Strategy Comparison in Patients Receiving Extracorporeal Life Support - A Prospective Observational Study
Purpose: The project aims to investigate the potential benefits of left ventricle (LV) venting/unloading for cardiogenic shock patients receiving veno-arterial extracorporeal life support (VA-ECLS).
ISHLT/ICCAC VAD Coordinator Career Development Grant
Given by ISHLT in partnership with the International Consortium of Circulatory Assist Clinicians (ICCAC)
Awarded to: Daphenie Fauvel, MSN, FNP-BC
Montefiore Medical Center in Bronx, NY USA
Research Title: No Patient Left Behind: Increasing VAD Patient Awareness & Access to Social Aid Programs
Purpose: The study will establish a novel post discharge social wellness visit to address patients declining engagement and concerns of extraordinary socioeconomic challenges.
ISHLT/Enduring Hearts Transplant Longevity Research Grant
Given by ISHLT in partnership with the funder, Enduring Hearts
Awarded to: Kaushik Amancherla, MD
Vanderbilt University Medical Center in Nashville, TN USA
Research Title: Molecular Insights into Early Cardiac Allograft Vasculopathy Using Single-Nuclear Multiomics
Purpose: The study is designed to identify important pathways and new drug targets to protect against cardiac allograft vasculopathy (CAV).
ISHLT Extracorporeal Photopheresis Immunomodulation in Thoracic Transplantation Challenge Grant, supported by Mallinckrodt Pharmaceuticals
Awarded to: Sonia Garg, MD
UT Southwestern Medical Center in Dallas, TX USA
Research Title: Description of the Effect of Extracorporeal Photopheresis on Markers of Cardiac Function, Net State of Immunosuppression and Microcirculatory Dysfunction
Purpose: The study will investigate the effect of immunomodulatory therapy (photopheresis) on cardiac function, markers of net state of immunosuppression, and microcirculatory dysfunction in heart transplant patients that have developed donor specific antibodies.
For more information about ISHLT and ISHLT Foundation Research Grants, visit here.