JHLT: The Podcast: Is Sotatercept Safe in Patients with PAH?
On this episode of JHLT: The Podcast, Ioana Preston, MD, joins to discuss the paper, "Efficacy and safety of sotatercept across ranges of cardiac index in patients with pulmonary arterial hypertension: A pooled analysis of PULSAR and STELLAR."
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Dr. Preston is the director of the pulmonary hypertension center at Lahey Hospital and Medical Center in Burlington, Massachusetts, and has over 20 years of experience caring for patients with PH, as well as multiple clinical trial sin PH.
The episode explores:
- What makes sotatercept unique as the first “biologic” in the treatment of PAH
- Hypotheses about the mechanism of action in sotatercept
- Sotatercept’s interaction with mPAP and what it indicates about the drug’s action on the pulmonary vasculature
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