ISHLT/O.H. Frazier Grant in MCS Translational Research



  O. H. "Bud" Frazier
Application Deadline:
16 January, 2023 at 11:59 p.m. EST


Purpose

The purpose of this grant is to support research utilizing MCS that would result in an increased understanding of the biologic effects, use as sole or combined therapy, insights into patient/MCS management, innovative use/application or improved outcomes for the treatment of heart failure.

Grant Details

This grant is aimed to support rising stars in the field of mechanical circulatory support at a critical time in their career. The Grant recipient will have already established a track record in the field of mechanical circulatory support and will aim to further develop their career in this area.

The intent is that the Grant will be for a junior faculty position dedicated to a career in the use of MCS as a treatment option for heart failure. It is anticipated that the individual will be clinician or clinician scientist at an active VAD/transplant program with a faculty appointment in either cardiology or cardiac surgery.

This is a one-year grant in the amount of $65,000.

 

  1. The applicant and the applicant's department head/division chief/research project director must be members of the ISHLT in good standing at the time of application and throughout the period of funding.
  2. The applicant must have Board certification or be Board eligible (within their stated field) and have an academic staff appointment.  
  3. Applicants must have achieved such no more than 3 years prior to the date of application.
  4. Applicants must have a full-time faculty appointment at a University or other accredited institution of higher learning.
  5. Applicants must not have already received extramural (external) funding >$40,000 for the same period from any other granting agency. Simultaneous internal funding for the recipient's institution/department is permitted if it is not for the same or closely related research.
  1. Research must begin between April 1 and December 31 of the grant year.     
  2. The Grant recipient is required to submit at least one abstract to the ISHLT Annual Meeting and one manuscript for publication in the JHLT related to the results of the funded research project.   
  3. The results of funded research cannot have been previously published or presented prior to publication in The Journal of Heart and Lung Transplantation or presentation at the ISHLT Annual Meeting.
  4. Funding will be awarded in two portions. 50% of the funding will be disbursed initially, with the remaining 50% disbursed upon submission of a progress report to the ISHLT Grants and Awards Committee 6 months after the date of initial funding. A final progress report and summary must be submitted to the ISHLT Grants and Awards Committee within 15 months of the initial disbursement.   
  5. The proportion of time to be devoted to clinical work and research for each recipient of the Grant should be determined by the recipient's Chair/Chief but not to exceed 50% devoted to research.
  6. Not more than 25% of the Grant may be used for salary support. The remainder is to be used for supplies and performing the research project. 
  7. $2000 of the Grant is to be allocated for support to travel to the following year's ISHLT meeting.
  8. The Grant recipient's institution agrees that the funds will be used to cover expenses for the purpose(s) described in the application, that there is not duplicate funding for these purposes, and that no portion of the grant will be used to pay for indirect costs, capital equipment purchases, or institutional overhead. ISHLT funds may not be used for the purchase of capital equipment.
  9. The Grant recipient's institution agrees to return any unused funds to the ISHLT.    
  10. Either at the time of application or by completion of the grant time period, it is expected that the Grant recipient will meet Joint Commission requirements or the equivalent regarding physician experience to manage/implant Ventricular Assist Devices ("VADs").   
  11. The Grant recipient will learn postoperative care and management of complications after VAD implant. 
  12. The Grant recipient will participate in educational and training programs for mechanical circulatory support. 
  13. The Grant recipient must be a member of ISHLT in good standing throughout the duration of the funding period. 
  14. The Grant recipient is expected to attend the annual ISHLT Scientific meeting during the grant period.
  15. ISHLT must be acknowledged as a funding source in all manuscripts and presentations derived from the funded research via the following statement: "This work was supported by the O.H. Frazier Award for Translational Research in MCS from the International Society for Heart and Lung Transplantation." Copies of these publications must be submitted to the ISHLT Headquarters office within 1 month of publication. 
  16. The Grant recipient or his/her research project director must be present at the Grants and Awards Presentation ceremony at the ISHLT Annual Meeting to receive acknowledgment of the award.

The scientific merit and fundability of all submitted research proposals will be judged by at least 2 members of the ISHLT Grants and Awards Committee. Outside experts may also be consulted. The Committee Chair will select the members to participate in the review process. All judges will independently review each research proposal according to established guidelines. A written report will be completed for each proposal. All reports will be sent to the Committee Chair. The Chair will organize a meeting or conference call to review the proposals and select the proposal(s) for funding. Applicants will not receive written feedback about their proposals, nor will proposals be returned to applicants. Depending upon the scope of applications received, funding may be awarded to a single application, or the funds may be allocated to two or more smaller, independent projects.


Current Grant Recipient


Supported by Abbott and Medtronic
Maziar Khorsandi, MD, FRCS c/Th
University of Washington Medical Center, Seattle, WA, USA
Project: "Utility of CardioMEMS HF system data in management of patients supported with durable left ventricular assist devices (LVAD) – implications for development of a closed-loop LVAD controller"