Volume 9 – Pulmonary Hypertension and Right Heart Failure

  Published: April 2015


Editors: Raymond L. Benza, MD; Paul A. Corris, MB, FRCP; Myung H. Park, MD; Patricia Uber, PharmD; James K. Kirklin, MD

Contributors (PDF)

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Table of Contents

Section I: Pulmonary Arterial Hypertension

Introduction - PAH: A Global Disease
Chapter 1: Classification and Epidemiology
Chapter 2: Genetics and Pathophysiology - Updates with Focus on Translational Approaches
Chapter 3: PAH Associated with Underlying Systemic Conditions
A. PAH and Connective Tissue Disease
B. PAH and Infectious Diseases
C. PAH and Congenital Heart Disease
D. PAH in Portopulmonary Hypertension
Chapter 4: Diagnosis of Pulmonary Arterial Hypertension


Section II: The Right Ventricle

Introduction - Nomenclature of Right Heart Failure
Chapter 5: Embryology, Anatomy and Function of Right Ventricle
Chapter 6: Mechanisms of Right Ventricular Failure
Chapter 7: Management of Right Heart Failure
Chapter 8: Determination of Right Ventricular Function in PAH

Section III: Medical Therapies for PAH

Introduction - The Journey of Medicines for PAH
Chapter 9: Therapies for PAH in the Developed and Developing World
Chapter 10: Combination Approach to Treatment for PAH
Chapter 11: Perspectives on Current Utilization of PAH Therapies and Future Treatments
Chapter 12: Assessing Prognosis and Response to Therapy


Section IV: Pulmonary Hypertension Associated with Heart and Lung Disease

Introduction - Effect of Pulmonary Hypertension in Systemic Disorders
Chapter 13: Pulmonary Hypertension in Left Heart Disease - Systolic, Diastolic, Valvular
Chapter 14: Pulmonary Hypertension in Parenchymal Lung Disease and Sleep Disorder
Chapter 15: Chronic Thromboembolic Pulmonary Hypertension

Section V: Preoperative Management of Patients with Pulmonary Hypertension


Introduction - Impact of Pulmonary Hypertension in Perioperative Settings
Chapter 16: Risk Assessment
Chapter 17: Anesthesia for Patients with Severe Pulmonary Hypertension and Right Heart Failure: Effects of Anesthetic and Resuscitation Drugs


Section VI: Surgical and Percutaneous Modalities for Pulmonary Hypertension and Right Heart Failure

Introduction - Unique Challenges in Mechanical Support for PH and Right Heart Failure
Chapter 18: Mechanical Ventilation in the Perioperative Period: Effects on the Right Ventricle
Chapter 19: Interventional Approaches for PAH
Chapter 20: Pulmonary Thromboendarterectomy
Chapter 21: Mechanical Circulatory Support for Right Heart Failure
Chapter 22: Lung Transplantation in Pulmonary Hypertension