Molecular Mechanisms of Allograft Injury and CLAD

Wednesday, September 30, 2020 4:00 – 5:30 p.m. EDT


 
Developed from ISHLT2020 Session 69 (ORAL)
 

Scientific Program

Moderators: Christopher H. Wigfield, MD, FRCS and Erika D. Lease, MD, FCCP

Welcome and Program Panel Introduction
Christopher H Wigfield, MD, FRCS, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

(256) Circulating Exosomes from Human Lung Transplant Recipients Having Respiratory Viral Infections Contain Nucleic Acids and Activate Signaling Pathways CGAS/STING and RIG-1
Sandhya Bansal, PhD, Norton Thoracic Institute / St. Joseph Hospital and Medical Center, Phoenix, AZ, USA

(254) Proteomics Analysis of Circulating Extracellular Vesicles Isolated from Plasma of Human Lung Transplant Recipients
Sandhya Bansal, PhD, Norton Thoracic Institute / St. Joseph Hospital and Medical Center, Phoenix, AZ, USA

(255) NanoString Gene Expression Profiling in Chronic Lung Allograft Dysfunction (CLAD)
Jamie L. Todd, MD, Duke University Medical Center, Durham, NC, USA

(259) Temporal Dynamics of the Pulmonary Microbiome after Lung Transplantation
Martin Watzenboeck, MD, Medical University of Vienna, Vienna, Austria

(25) Gene Expression Differences between DCD and DBD Lungs are Mitigated by Ex Vivo Lung Perfusion (EVLP)
Jonathan D. Allen, Latner Thoracic Research Laboratories / UHN, Toronto, ON, Canada

(260) A Multi-Center Study of BAL CXCR3 Chemokines during Allograft Injury after Lung Transplantation
Michael Y. Shino, MD, UCLA, Los Angeles, CA, USA

Live Q&A Segment with All Presenters
Led by Erika D. Lease, MD, FCCP, University of Washington, Seattle, WA, USA

ISHLT Advanced Lung Failure and Transplantation Interdisciplinary Network Update
Glen Westall, FRACP, PhD, The Alfred Hospital, Melbourne, Australia
Chair, Advanced Lung Failure and Transplantation Interdisciplinary Network Steering Committee

ISHLT Announcements
Greg Schultz, CAE, Chief Executive Officer, ISHLT, Addison, TX, USA
 

Continuing Education Information

Learning Objectives – At the conclusion of this session attendees will increase their knowledge, performance and/or practice by listening to six presentations based on submitted research abstracts that were to be presented at the 2020 ISHLT Scientific Annual Meeting. The presenters will be disseminating data as it relates to Molecular Mechanisms of Allograft Injury and CLAD. Abstracts have been peer reviewed.

Target Audience – The target audience includes physicians, surgeons, scientists, pharmacists, nurses, transplant coordinators and other allied health and social science professionals engaged in the management and treatment of patients with advanced heart or lung disease, basic science or clinical research related to these fields, or other specialties which cause them to become involved in the treatment of patients with advanced heart or lung disease.

Activity Designed to Change – This activity is designed to improve knowledge and competence and performance.

Learning Attributes   Patient Care and Medical Knowledge

Disclosures – Current guidelines state that participants in continuing medical and allied health professional education activities must be made aware of any affiliation or financial interest that may affect the program content or a speaker’s presentation. Planners, Faculty and Chairs participating in this meeting are required to disclose to the program audience any real or apparent conflict(s) of interest related to the content of their presentation or service as Chair/Planner. Disclosures will be distributed in the Learner Notification that you receive as a participant prior to the live virtual session. Additionally, all speakers have been asked to verbally disclose at the start of their presentation any financial interest or affiliations and to indicate if a product they are discussing is not labeled for the use under discussion or is still investigational.

Disclaimer – The information presented in this activity represents the opinion of the faculty and is not necessarily the official position of the ISHLT.

Documenting CME Credits – The ISHLT provides CME certificates to those who have participated in an ISHLT educational activity. The ISHLT does not submit credits to regulating bodies or certifying organizations on behalf of the participants. It is the participants responsibility to submit proof of credits on his or her own behalf.
 

ACCME Accreditation

Physicians

Accreditation Statement – The International Society for Heart and Lung Transplantation (ISHLT) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation Statement – ISHLT designates this live virtual activity for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses and Pharmacists

In support of improving patient care, this activity has been planned and implemented by Amedco LLC and The International Society for Heart and Lung Transplantation (ISHLT). Amedco LLC is jointly accredited by the American Council for Continuing Medical Education (ACCME) the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Credit Designation Statement – Amedco LLC designates this live activity for a maximum of 1.5 contact hours for nurses. Knowledge-based CPE contact hours for pharmacists are being reviewed for possible eligible credit.

Nurse Practitioners

The American Association of Nurse Practitioners (AANP) recognizes the Accreditation Council for Continuing Medical Education (ACCME) and the American Nurses Credentialing Center (ANCC) as approved accreditors and allow reciprocity for AANPCP continuing education.

Transplant Coordinators Credit

As a designated Approved Provider by the American Board for Transplant Certification (ABTC), the International Society for Heart and Lung Transplantation grants up to 1 Category 1 Continuing Education Points for Transplant Coordinators (CEPTCs) for this offering. CEPTC Approval Number: 221-09.