7:55 – 8:00 a.m.
WELCOME AND OVERVIEW
Academy Chairs
8:00 – 9:00 a.m.
SESSION 1 – HEART FAILURE: OVERVIEW AND EVALUATION
Chair: Anique Ducharme, MD, MSC, Montréal Heart Institute, Montréal, Canada
8:00 a.m. – Case Presentation (3 minutes)
Jacinthe Boulet, MD CM, FRCPC, Harvard Medical School, Boston, MA, USA
8:03 a.m. – Heart Failure: General Overview and Concepts (12 minutes)
Sonia Mirabet Perez, MD, Hospital Sant Pau, Barcelona, Spain
Teaching/Discussion Points
- Scope of the problem
- Pathophysiology
- Causes of heart failure
- Multidisciplinary Team Approach, Patient partnership
8:15 a.m. – Evaluation of Patients with Heart Failure (15 minutes)
Michelle Kittleson, MD, PhD, Cedars Sinai Heart Institute, Los Angeles, CA, USA
Teaching/Discussion Points
- Signs and symptoms
- Biomarkers
- Screening guidelines
- Risk stratification
- Indicators for advance therapy referral
8:30 a.m. – Heart Failure Tests (15 minutes)
Marco Masetti, MD, PhD, University of Bologna, Bologna, Italy
Teaching/Discussion Points
- Role of right heart catherization and hemodynamic monitoring
- Cardiopulmonary exercise testing interpretation
- When to perform endomyocardial biopsy
- Ischemia evaluation
- Added benefits of MRI
- Genetics?
8:45 a.m. – Q&A with Panel (15 minutes)
9:00 – 10:15 a.m.
SESSION 2 – MANAGEMENT OF PATIENTS WITH ADVANCED HEART FAILURE and SHOCK
Chair: Alejandro M. Bertolotti, MD, Hospital Universitario Fundacion Favaloro, Buenos Aires, Argentina
9:00 a.m. – Case Presentation (3 minutes)
Jacinthe Boulet, MD CM, FRCPC, Harvard Medical School, Boston, MA, USA
9:03 a.m. – Non-Pharmacologic and Pharmacologic Management (15 minutes)
Michelle Kittleson, MD, PhD, Cedars Sinai Heart Institute, Los Angeles, CA, USA
Teaching/Discussion Points
- Sodium and fluid management
- Risk factor modification (obesity, inactivity, sleep apnea, HTN, DM, smoking)
- Guideline recommendations
- Update on novel therapeutic approaches
- Palliative care Home inotropes
9:18 a.m. – Principles for Arrhythmia Management and Electrical Devices (12 minutes)
Eileen Hsich, MD, Cleveland Clinic, Cleveland, OH, USA
Teaching/Discussion Points
- Atrial fibrillation management
- Ventricular arrhythmias
- Implantable cardioverter-defibrillator
- Cardiac resynchronization therapy
9:30 a.m. – Surgical/interventional Management of Heart Failure (15 minutes)
Ivan Knezevic, MD, PhD, University Medical Centre Ljubljana, Ljubljana, Slovenia
Teaching/Discussion Points
- The concept of Heart Team
- Coronary Disease: High risk PCI vs. surgical revascularization
- Valve Disease: Surgical options
- Transcatheter Edge to Edge Repair and other percutaneous devices for Valves Disease Management
9:45 a.m. Cardiogenic Shock (15 minutes)
Jerry Estep, MD, Cleveland Clinic, Cleveland, OH, USA
Teaching/Discussion Points
- Recognition of shock
- SCAI classification and outcomes
- Short term options for mechanical circulatory support (algorithm: intra-aortic balloon pump, ECMO, percutaneous mechanical circulatory support)
10:00 a.m. – Q&A with Panel (15 minutes)
10:15 – 10:45 a.m.
COFFEE BREAK
10:45 a.m. – 12:00 p.m.
SESSION 3 – CARDIAC TRANSPLANTATION AND ALTERNATIVES
Chair: Yael Peled, MD, Sheba Medical Center, Tel Aviv, Israel
10:45 a.m – Case Presentation (3 minutes)
Eyal Nachum, MD. Sheba Medical Center, Tel Aviv, Israel
10:48 a.m. – Consideration for Advanced Heart Failure Therapies (17 minutes)
Marco Masetti, MD, PhD, University of Bologna, Bologna, Italy
Teaching/Discussion Points
- Timing of referral
- Special considerations (including Group O, large body habitus)
- Volume and center’s experience
11:05 a.m. – Pulmonary Hypertension: Pulmonary Arterial Hypertension in Heart Failure (15 minutes)
Maxime Tremblay-Gravel, MD, MSc, Montréal Heart Institute, Montréal, Canada
Teaching/Discussion Points
- Definition
- WHO classification
- Etiologies
- Medical therapies
- Procedures and Monitoring
11:20 a.m. – Evaluation of the Transplant Candidate (25 minutes)
Anique Ducharme, MD, MSC, Montréal Heart Institute, Montréal, Canada
Teaching/Discussion Points
- Multidisciplinary approach of heart transplant candidates
- Indications for transplant
- Contraindications for transplant
- Evaluation process (Guidance for screening grids and serial pre-transplant evaluation)
- RHC interpretation
- Substance abuse, tobacco use, and cannabis
11:45 a.m. – Q&A with Panel (15 minutes)
12:00 – 1:00 p.m.
LUNCH BREAK
1:00 – 1:45 p.m.
SESSION 4 – CARDIAC TRANSPLANTATION – SPECIAL CONSIDERATIONS
Chair: Anique Ducharme, MD, MSC, Montréal Heart Institute, Montréal, Canada
1:00 p.m. – Difficult Decision Making (15 minutes)
Anique Ducharme, MD, MSC, Montréal Heart Institute, Montréal, Canada
Teaching/Discussion Points
- Restrictive and infiltrative cardiomyopathies
- Chagas Disease
- Retransplantation
- Considerations for multi organ transplant
1:15 p.m – The Nightmare of Pediatric and Adult Congenital Disease (15 minutes)
Lori West, MD, DPhil, Alberta Transplant Institute, Edmonton, AB, Canada
Teaching/Discussion Points
- Pediatric transplantation
- Adult congenital patient
1:30 p.m. – Q&A with Panel (15 minutes)
1:45 – 3:45 p.m.
SESSION 5 – GUIDING PRINCIPLES: DONOR RECIPIENT MATCH and IMMUNOLOGY 101
Chair: Yael Peled, MD, Sheba Medical Center, Tel Aviv, Israel
1:45 p.m. – Case Presentation (3 minutes)
Mónica Gilbert, MD, Clinica Guayaquil, Guayas, Ecuador
1:48 p.m. – Balancing the Risk (20 minutes)
Yael Peled, MD, Sheba Medical Center, Tel Aviv, Israel
Teaching/Discussion Points
- Donor risk factors
- Recipient risk factors in the context of donor heart selection
- Balancing donor and recipient risk in donor selection (Ischemic Time & Risks score)
- Extended criteria donor hearts (including DCD donor and Ex-Vivo Perfusion)
2:08 p.m. – Heart Transplant Procedure: Pre, Intra and Postoperative Aspects of Care (17 minutes)
Alejandro M. Bertolotti, MD, Hospital Universitario Fundacion Favaloro, Buenos Aires, Argentina
Teaching/Discussion Points
- Patient prioritization and risk stratification
- Technical aspects of heart transplant procedure
- Postoperative care: common scenarios
- Primary Graft Dysfunction: diagnosis and management
2:25 p.m. – Overview of Transplantation Immunobiology (20 minutes)
Jon Kobashigawa, MD, Cedars Sinai Heart Institute, Los Angeles, CA, USA
Teaching/Discussion Points
- Immunology 101
- Immunosuppression strategies
- Sensitized patient
2:45 p.m. – Disease Management Strategies (Rejection, Immunosuppression, Infections and Complications) (15 minutes)
Eileen Hsich, MD, Cleveland Clinic, Cleveland, OH, USA
Teaching/Discussion Points
- Rejection surveillance and treatment
- Common infectious considerations
- Common medical complications (bone disease, etc.)
3:00 p.m. – Special Consideration of Immunosuppression (20 minutes)
Jon Kobashigawa, MD, Cedars Sinai Heart Institute, Los Angeles, CA, USA
Teaching/Discussion Points
- Pros and Cons of Induction therapy
- Minimizing Immunosuppression, including steroid withdrawal/avoidance
3:20 p.m. – Q&A with Panel (15 minutes)
3:35 – 4:05 p.m.
COFFEE BREAK
4:05 – 5:10 p.m.
SESSION 6 – MECHANICAL CIRCULATORY SUPPORT
Chair: Alejandro M. Bertolotti, MD, Hospital Universitario Fundacion Favaloro, Buenos Aires, Argentina
4:05 p.m. – Case Presentation (3 minutes)
Eyal Nachum, MD, Sheba Medical Center, Tel Aviv, Israel
4:08 p.m. – Current Devices and Outcomes (22 minutes)
Alejandro M. Bertolotti, MD, Hospital Universitario Fundacion Favaloro, Buenos Aires, Argentina
Teaching/Discussion Points
- History of device development (very brief)
- Continuous vs Pulsatile devices
- Axial vs Centrifugal flow
- TAH versus BiVAD
- Scoring systems (RV and bleeding)
- Candidate selection
4:30 pm. – Chronic Complications in Mechanical Circulatory Support (20 minutes)
Diyar Saeed, MD, PhD, Leipzig Heart Center, Leipzig, Germany
Teaching/Discussion Points
- GI bleeding
- CVA
- Driveline infections
- Aortic insufficiency
- Pump thrombosis
- Late RV failure
4:50 p.m. – Q&A with Panel (20 minutes)
5:10 – 5:15 p.m.
COURSE SUMMARY AND EVALUATION
Anique Ducharme, MD, MSC, Montréal Heart Institute, Montréal, Canada
5:15 p.m.
ADJOURN