THIS MONTH'S FOCUS:

PULMONARY HYPERTENSION AND
PULMONARY TRANSPLANTATION

(PDF VERSION)


Many thanks to Veronica Franco and Tereza Martinu (PH and PULM TX Council Links Liaisons) for coordinating the focus content for this issue.




VINCENT'S PHOBOPHOBIC SENSE:

What do you get when you cross Ben Franklin and luck? Diligence. Ben Franklin has given us many pithy quotes. We know from Louis Pasteur, "fortune and chance favor the prepared mind." Our first American always gazing at us from the U.S. one-hundred dollar bill gives us the idiom, "diligence is the mother of good luck." In this issue Herman Reichenspurner provides us with the dividend of 30 years of diligence. links imageJohn Haney and Matthew Hartwig from Duke reincarnate Dr Franklin into a cardiothoracic surgeon diligently adding life to our lung recipients. We anxiously await the results of the RESULT trial to see if the Nissen fundoplication procedure can alter the natural history of BOS.

From the Pulmonary Hypertension Council we are provided timely updates and the tremendous progress that has been made for our sufferers of pulmonary hypertension, as the late Dr Eugene Robin would refer to over 30 years ago as, "denizens of the near dead." Sorry about the macabre association with Halloween and the recent rage from the cinema about World War Z (if you're familiar with this movie, there are "endless" examples of diligence). Nevertheless, pulmonary hypertension patients did not do so well in the past. However, today they are very much alive, quite functional and out of the "valley of Death". Be sure not to miss their "Nice" update from the 5th World Symposium on Pulmonary Hypertension, Progress in PAH Prognostics and Therapy: Improving the State of the Disease, and The New Face of PAH.

On a lighter side, the Pulmonary Council teases us about lung transplantation in California led by the surf of San Diego. This has nothing to do with penguins, I think. And Jim George's article on Writing a Successful Abstract is sure to help you get a ticket to the surf all on your own.

Lastly, be careful of being blind-sided by Coke, Soda, Pop or Sodi-Pop and by those who claim to have your back. Recall from 2009, The Blind Side, Sandra Bullock and the words of Alfred Lord Tennyson ... Theirs not to make reply, Theirs not to reason why, Theirs but do and die.... According to Michael Oher in The Blind Side, he believes Tennyson wrote for us to try for courage and hope for honor. And that our leaders, chiefs, chairpersons, administrators, managers, advisors, coaches or quarterbacks are not left "spineless" and actually have the same courage and honor when we have their backs and of course, vice versa. Is it just fear of fear itself or are we just one of 600.

Happy October

Vincent Valentine, MD
Editor-in-Chief, ISHLT Links Newsletter



IN THE SPOTLIGHT:


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Stay Classy, San Diego!

by Jason Christie, MD

"Stay classy, San Diego!" I am reminded of these words spoken by Ron Burgundy from the movie Anchorman as I sit writing this description of the 2014 ISHLT program on a warm sunny early autumn day in Philadelphia, with crisp air and bluebird skies. I feel compelled to find some way to get outside and enjoy each moment of it, because days like these in the U.S. Northeast are like breaths or heartbeats - we only get so many. Not so in the beautiful microclimate in San Diego: the site of the 2014 ISHLT conference. Yet, as we know from previous ISHLT conferences in this beautiful city, San Diego offers so many more attractions beyond its stellar weather. Read more →



FOCUS ON PULMONARY HYPERTENSION:



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Nice 5th World Symposium on Pulmonary Hypertension Report

by Veronica Franco

As a participant in the 5th World Symposium on Pulmonary Hypertension (WSPH), held February 2013 in Nice, France, I was struck by several things—first was the beautiful scenery. The best of Nice: breathing fresh Mediterranean air while walking along the Promenade des Anglais, viewing the deep blue waters of the Cote d'Azur with an eagle eye view of the whole city from atop Castle Hill, eating exquisite Gelato and French cuisine, and best just sitting at a café at Plaza Massena and relaxing. Nice is one of my favorite places to visit, thus, is not surprising the ISHLT board of directors choose this amazing city for their meeting in 2015. Read more →



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Progress in PAH Prognostics and Therapy: Improving the State of the Disease

by Richa Agarwal

Pulmonary arterial hypertension is a progressive, fatal disease characterized by progressive vascular proliferation and remodeling of the pulmonary arteries (PA), ultimately leading to increased pulmonary vascular resistance (PVR) and right sided heart failure (RHF). The field of PAH has seen remarkable improvements in patient outcomes, owing to heightened awareness with emphasis on earlier diagnosis and referral, creation of predictive models for disease progression and prognostication, as well as advancements in drug therapy. Read more →



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The New Face of Pulmonary Arterial Hypertension

by Thenappan Thenappan, MD

Pulmonary arterial hypertension (PAH) is characterized by proliferation and remodeling of the small pulmonary arteries, leading to increased pulmonary vascular resistance and ultimately right ventricular failure and death. The classic textbook description of idiopathic pulmonary arterial hypertension is it more commonly affects middle-aged female. Read more →



FOCUS ON PULMONARY TRANSPLANTATION:



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Lung Transplantation in California

by David Weill

Like so much else, organ transplantation in California benefits from an abundance of riches. With great beaches and weather, vibrant cities, the movie industry, and a bountiful agricultural climate (especially for grapes), California is certainly a land of plenty. And did I mention the food? Any type of food is available from the chic restaurants in Los Angeles to the culinary creativity of San Francisco (which many consider the second best dining city in the country - do you even need to ask? New Orleans). So with all this going in its favor, and with a population of nearly 40 million people to support a robust organ donor and patient referral base, there are not surprisingly several active lung transplant programs. Read more →



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Surf's Up: The World's Top 10 Cardiothoracic Transplant Programs

compiled by Daniel Chambers and Tereza Martinu

Many key performance indicators can be used to rate the success of individual programs: survival, transplant numbers, donor utilisation, research output, etc. But one potentially important criterion has been completely neglected in the literature (and notably by Marshall and Josef in the ISHLT Registry): the quality of the local surf-break. We decided to rectify this oversight. Read more →



Nissen Fundoplication and Lung Transplantation

by John Haney and Matthew Hartwig

"An ounce of prevention is worth a pound of cure" - Benjamin Franklin. If the esteemed Mr. Franklin were a lung transplant surgeon, certainly one at the writers' institution, he might have rephrased his sentiment, "an early Nissen is better than a late retransplant." Read more →



OF SPECIAL INTEREST:



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How Lucky ... to be President-Elect of the ISHLT!

by Hermann Reichenspurner

While rotating on my student elective at Stanford University Hospital in 1982, the transplant group within the department was very excited that there was a new scientific society focusing only on heart transplantation. Two years later in New York City in 1984, I attended my first Society meeting and presented my thesis on "Cyto-immunological monitoring after heart transplantation." At that time the Society was called the International Society for Heart Transplantation. Read more →



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Writing a Successful Abstract

by Jim George

Attending annual meetings are an important part of professional life. It is an opportunity to meet other professionals face-to-face and to present research or ideas to a critical audience. While meeting people is easy enough, getting on the program of a clinical/scientific meeting involves convincing a committee of abstract reviewers that your work is of high enough quality and sufficiently interesting to warrant giving it one of a finite number of slots available for presentation. Read more →



NEWS AND ANNOUNCEMENTS:



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2014 ISHLT SAN DIEGO

You are invited to submit your best science for presentation at the 34th Annual Meeting & Scientific Sessions, April 10-13, 2014 at the Manchester Grand Hyatt San Diego. The Abstract Submission Site is live at www.ishlt.org. Abstract Submission deadline is November 15, 2013 at 11:59 PM EST. Registration and housing for the Annual Meeting and the Academies will be available online in October 2013. Check the ISHLT web site for details.



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ISHLT Grants and Awards Program

The 2014 ISHLT Grants and Awards applications will be available online November 1, 2013. For general information, funding stipulations/award policies and the grant applications/instructions, go to the ISHLT Website at www.ishlt.org. Click on "Awards" to access the information. Deadline for receipt of applications is Wednesday, January 15, 2014. Grants will be awarded at the ISHLT 34th Annual Meeting and Scientific Sessions, April 10-13, 2014 in San Diego, California. For 2014 info, visit: 2014 Grants and Awards Program. Also, view a Special Invitation for JFTC members.



LAUGHING LINKS:


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35 Terrible Puns to Brighten Your Day

by Dan Dilling

Everybody loves a good pun. Here are 35 to brighten your day. Some of these were quite sophisticated and even multi-media! Read more →



OUTTA THIS WORLD LINKS:


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Interesting, Inspiring and Intriguing Links from Around the Globe

Hot topics in organ transplantation this month include stories from Australia, Canada, Costa Rica, the United Kingdom, and the United States. Read more →



TATTLING LINKS:


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ISHLT Members in the News

Some of our ISHLT members from all over the world have been found in the news this month, including Robert Weintraub (Australia), Terrence Yau (Canada), Paul Ramesh Thangaraj (India), Mordechai Kramer (Israel), Steven Tsui (United Kingdom), and Kalpaj Parekh, Richard Ha, Marie Budev, Sanjeev Aggarwal, Asghar Khaghani, Theodore Boeve, Tomasz Timek, O Howard Frazier, H Todd Massey, Jondavid Menteer, Thomas Wozniak, Abbas Ardehali, Navin Rajagopalan, Charles Hoopes, David D'Alessandro and Jacqueline Lamour (United States). Read more →



EDITOR'S CORNER


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Coke, Soda, Pop or Sodi-Pop

by Vincent Valentine

In the last month's issue of the Links on English, Communication and Confusion, we barely scratched the surface about the distinct Englishes across the globe in an effort to increase our awareness of the differences that could simultaneously improve communication and add to confusion. To further lead you into "muddy waters" on this issue and in this issue of the Links, we will look at some of the dialects (regional variations of terms) used across the United States. Yet this is another example of the importance of appreciating the variations of the English language to improve communication. Read more →



WORD OF THE MONTH:


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"Diligence"

Noun: persevering application; devoted and painstaking application to accomplish an undertaking.
(From Merriam-Webster's Third New International Dictionary of the English Language Unabridged, 2002.) Also, specifically in France it is a large closed public horse-drawn carriage formerly used for long journeys. Car may be short for carriage and because of the oppressive heat and humidity of the Southeastern United States there were "open cars" pulled by our equine friends before the automobile as there were "open cars" pulled by steam engine locomotives on the rail lines. After an evening and humid journey by horse and buggy when you disembarked you had to "get down from the car." More on this in the Editor's Corner.




Contact

Vincent G Valentine, MD, Editor-in-Chief
vgvalent@utmb.edu

Editorial Staff


"Action speaks louder than words but not nearly as often."

— Mark Twain

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Disclaimer: Any opinion, conclusion or recommendation published by the Links is the sole expression of the writer(s) and does not necessarily reflect the views of the ISHLT.